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INCORPORATE IN NORTH AMERICA

Registration address

1260 E Locust St. Suite 302 Ontario, California 91761,United States

Operation Address

Local Business 702-350-7698
Email info@genabolix.com
sales@genabolix.com
Service Email service@genabolix.com
Customer Service customer@genabolix.com
510-431-9888

SHANGHAI OFFICE

Address

Room 1604,Block B,NewCaohejing International Business Center, No.391 Gui Ping Road,Shanghai 200233,China

Office Phone 0086-21-60904639
Email info@genabolix.com
sales@genabolix.com
Customer Service customer@genabolix.com
510-431-9888

Genabolix Canada office

Address

1405-5288 Melbourne Street, Vancouver V5R 6E6, Canada

Email: sales@genabolix.com
Customer Service: customer@genabolix.com
510-431-9888

Genabolix Europe office

Address

Grensstraat 4, 4645 BS Putte, The Netherlands (Nederland)

Attn: Jan de Heij
Tel: 00 31 (0)164603336
Email: jan@genabolix.com
Customer Service: customer@genabolix.com
510-431-9888

Genabolix South Africa office

Address

Rivonia Boulevard, Rivonia Road, Sandton, Johannesburg South Africa

Attn: Raj Bachulal
Tel: +27824805900
Email: raj@genabolix.com
Customer Service: customer@genabolix.com
510-431-9888

D-Serine

The mammalian brains unusually contain high levels of D-serine, a D-amino acid previously thought to be restricted to some bacteria and insects. In the last few years, studies from several groups have demonstrated that D-serine is a physiological co-agonist of the N-methyl D-aspartate (NMDA) type of glutamate receptor, a key excitatory neurotransmitter receptor in the brain. D-Serine, rather than glycine as originally thought, binds with high affinity to the glycine site of NMDA receptors and, along with glutamate, mediates several important physiological and pathological processes, including NMDA receptor (NMDAR) transmission, synaptic plasticity and neurotoxicity.

Two discoveries have put D-serine in the spotlight of neuroscience.

First, D-serine was detected in brain tissue at high levels. It is synthesized in types of brain cells called astrocytes, and its production is essential in the process of long-term potentiation. Long-term potentiation is a process wherein neurological pathways are enhanced in response to certain environmental stimuli – in other words it is the process by which long term memories are consolidated in the brain. Administration of D-Serine leads to accumulation of the amino acid in the cerebral cortex and hippocampus. These are areas of the brain involved in memory consolidation, and D-Serine acts via NMDA receptors on neurons in these areas.

Second, it was found to act on the N-methyl-D-aspartate receptor (NMDAR). This receptor is central to use-dependent synaptic plasticity, the cellular process which is widely believed to underlie learning.

Administration of D-Serine has been demonstrated to enhance learning and working memory. In summary, D-Serine can be used to optimize the brain's ability to learn and recall complex functions and may be a valuable asset to students, workers, or anyone who may have to process or memorize difficult material.

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